NLRP3 Plays a Key Role in Antihelminth Immunity in the Enteral and Parenteral Stages of Trichinella spiralis-Infected Mice-Reference-Cited by-同舟云学术

NLRP3 Plays a Key Role in Antihelminth Immunity in the Enteral and Parenteral Stages of Trichinella spiralis-Infected Mice

Published:2023-04-18 Issue:4 Volume:91 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Pan Tian-Xu¹²³,Huang Hai-Bin¹²³,Lu Hui-Nan¹²³,Zhao Guang-Xun¹²³,Quan Yu¹²³,Li Jun-Yi¹²³,Xue Ying¹²³,Zhu Zhi-Yu¹²³,Wang Yue¹²³,Shi Chun-Wei¹²³,Wang Nan¹²³,Yang Gui-Lian¹²³^ORCID,Wang Chun-Feng¹²³

Affiliation:

1. College of Veterinary Medicine, Jilin Agricultural University, Changchun, China

2. Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding, Jilin Agricultural University, Changchun, China

3. Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China

Abstract

Trichinellosis is an important foodborne zoonosis, and no effective treatments are yet available. Nod-like receptor (NLR) plays a critical role in the host response against nematodes.

Funder

National Natural Science Foundation of China

Science and Technology Development Program of Ji Lin Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00382-22

Reference40 articles.

1. A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice

2. Molecular identification of Trichinella spiralis nudix hydrolase and its induced protective immunity against trichinellosis in BALB/c mice

3. Mapping of the complement C1q binding site on Trichinella spiralis paramyosin

4. Heart- and skeletal muscle-specific antigens recognized by trichinellosis patient sera

5. Production of IL-1β and Inflammasome with Up-Regulated Expressions of NOD-Like Receptor Related Genes in Toxoplasma gondii-Infected THP-1 Macrophages

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