Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers-Reference-Cited by-同舟云学术

Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers

Published:2022-04-21 Issue:4 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Barton Amber¹²^ORCID,Hill Jennifer¹,Bibi Sagida¹,Chen Liye³,Jones Claire¹,Jones Elizabeth¹,Camara Susana¹,Shrestha Sonu¹,Jin Celina¹,Gibani Malick M.¹⁴,Dobinson Hazel¹,Waddington Claire¹⁵,Darton Thomas C.¹⁶⁷,Blohmke Christoph J.¹,Pollard Andrew J.¹

Affiliation:

1. Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom

2. Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom

3. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

4. Department of Infectious Disease, Imperial College London, London, United Kingdom

5. Department of Medicine, University of Cambridge, Cambridge, United Kingdom

6. Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom

7. Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom

Abstract

Infections with Salmonella enterica serovars Typhi and Paratyphi A cause an estimated 14 million cases of enteric fever annually. Here, the controlled nature of challenge studies is exploited to identify genetic variants associated with enteric fever susceptibility.

Funder

Wellcome Trust

Bill and Melinda Gates Foundation

European Commission

NIHR | NIHR Oxford Biomedical Research Centre

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00389-21

Reference64 articles.