Novel replicative properties of a capsid mutant of bacteriophage phi chi 174

Author:

Vito C C,Dowell C E

Abstract

A capsid mutant of bacteriophage phi chi 174 demonstrates altered requirements for the conversion of viral single-stranded DNA to double-stranded replicative form DNA. In the presence of puromycin at 42 C, wild-type phi chi 174 is unable to complete this replicative event, whereas phi chi ahb is able to do so. Furthermore, in contrast to wild-type phi chi 174, formation of phi chi ahb parental replicative form DNA is sensitive to rifampin under certain experimental conditions. These data suggest that the mutant capsid proteins of phi chi ahb influence the biosynthesis of phi chi ahb complementary strand DNA.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference37 articles.

1. Mutant of bacteriophage 4)X174 which infects Escherichia coli K12 strains. H. Replication of 4XtB on ts DNA Strains;Bone D.;Virology,1973

2. Isolation and characterization of prototrophic mutants ofEscherichia coli unable to support the intracellular growth of T7;Chamberlin M.;J. Virol.,1974

3. An S13 capsid mutant that makes no replicative form DNA;Doninger J.;Virology,1969

4. Dressier D. 1975. The recent excitement in the DNA growing point problem p. 552-554. In M. P. Starr J. L. Ingraham and S. Raffel (ed.) Annual review of microbiology vol. 29. Annual Reviews Inc. Palo Alto Calif.

5. Inhibition of bacteriophage 4X174 DNA replication in dnaB mutants of Escherichia coli C;Dumas L. B.;J. Virol.,1974

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Growth and DNA synthesis of bacteriophage phi x174 in a dnaP mutant of Escherichia coli;Journal of Virology;1979-06

2. Bacteriophage ΦX174 growth in an Escherichia coli dnaIts mutant, KS810;Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis;1978-02

3. RNA Polymerase of Escherichia coli;Current Topics in Microbiology and Immunology;1978

4. The Isometric Single-Stranded DNA Phages;Comprehensive Virology;1977

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3