Characterization of the trehalose 6,6'-dimycolate surface monolayer by scanning tunneling microscopy-Reference-Cited by-同舟云学术

Characterization of the trehalose 6,6'-dimycolate surface monolayer by scanning tunneling microscopy

Published:1994-02 Issue:2 Volume:62 Page:754-756
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Schabbing R W¹,Garcia A¹,Hunter R L¹

Affiliation:

1. Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia 30322.

Abstract

The toxicity of trehalose 6,6'-dimycolate (TDM), a glycolipid of mycobacteria, requires presentation as a surface monolayer. Our model of the structure of the TDM monolayer was confirmed and extended by scanning tunneling microscopy. It consists of linear arrays with a periodicity of approximately 90 A (9 nm) that clustered in groups of four to form secondary structures with a periodicity of 360 A (36 nm).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.62.2.754-756.1994

Reference17 articles.

1. Behling C. A. 1992. Studies on the composition conformation and function of lipids on the surface of mycobacteria. Ph.D thesis Emory University Atlanta Ga.

2. Development of a trehalose 6,6'-dimycolate model which explains cord formation by Mycobacterilum tuberculosis;Behling C. A.;Infect. Immun.,1993

3. Induction of pulmonary granulomas, macrophage procoagulant activity and tumor necrosis factor-alpha by trehalose glycolipids;Behling C. A.;Ann. Clin. Lab. Sci.,1993

4. Bloch H. 1950. Studies on the virulence of tubercle bacilli: 756 NOTES

5. Studies on the virulence of tubercle bacilli. Variations in the virulence effect elicited by Tween 80 and thiosemicarbazone;Bloch H.;Br. J. Exp. Pathol.,1953

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