Nutritional requirements for growth of uropathogenic Escherichia coli in human urine-Reference-Cited by-同舟云学术

Nutritional requirements for growth of uropathogenic Escherichia coli in human urine

Published:1997-05 Issue:5 Volume:65 Page:1960-1961
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Hull R A¹,Hull S I¹

Affiliation:

1. Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

Abstract

Enrichment with D-cycloserine was used to identify Escherichia coli auxotrophic mutants that exhibited limited growth in human urine. Bacterial synthesis of guanine, arginine, and glutamine was found to be required for optimal growth in urine. Mutants that required leucine, methionine, serine, phenylalanine, or proline also exhibited reduced growth in urine. Several other nutritional mutants, including nicotinamide auxotrophs, which are found frequently among cystitis isolates, exhibited normal growth in urine.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.65.5.1960-1961.1997

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