Antigen distribution in a latex suspension and its relationship to test sensitivity

Author:

Hechemy K,Stevens R W,Gaafar H A

Abstract

Specific aggregation of latex particles due to antigen-antibody reaction occurred only when antigen was latex bound, as found in a study using Escherichia coli 0111:B4 extract. Maximum serological sensitivity was achieved when free antigen was present in a narrow range of ratios with the bound antigen.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference10 articles.

1. A histoplasminlatex agglutination test. I. Results with animal serum;Carlisle H. N.;J. Lab. Clin. Med.,1958

2. Agglutination of latex particles without antigen adsorption;Donaldson P.;J. Immunol.,1965

3. Measurement of beta activities in aqueous samples utilizing Cerenkov radiation;Haberer K.;Packard Technical Bull.,1966

4. Detection of Escherichia coli antigens by a latex agglutination test;Hechemy K.;Appl. Microbiol.,1974

5. Latex test for quantitative determination of Escherichia coli antibody;Hechemy K.;Appl. Microbiol.,1974

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