Effect of Escherichia coli Heat-Stable Enterotoxin on Cyclic GMP Levels in Mouse Intestine

Author:

Newsome P.M.1,Burgess M.N.1,Mullan N.A.1

Affiliation:

1. Beecham Pharmaceuticals Research Division, Nutritional Research Centre, Walton Oaks, Tadworth, Surrey, England

Abstract

Partially purified heat-stable enterotoxin obtained from Escherichia coli strain F11/P155 caused an accumulation of cyclic GMP in the intestines of 8-day-old mice.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference15 articles.

1. Burgess M. N. R. J. Bywater C. M. Cowley N. A. Mullan and P. M. Newsome. 1978. Biological evalu-NOTES 291

2. ation of a methanol-soluble heat-stable Escherichia

3. coli enterotoxin in infant mice pigs rabbits and calves.

4. Infect. Immun. 21:526-531.

5. Differences in the response of rabbit small intestine to heat-labile and heat-stable enterotoxins of Escherichia coli;Evans D. G.;Infect. Immun.,1973

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