Abstract
Bacteriophage E79 was shown to interact with the lipopolysaccharide (LPS) of Pseudomonas aeruginosa strain PAO. LPS isolated from an E79-sensitive, smooth strain inactivated the phage, exhibiting a Phl50 value (concentration of LPS that caused a 50% decrease in the titer of phage during 1 h of incubation at 37 degrees C) of 0.04 microgram/ml, whereas the LPS isolated from a rough mutant derived from the wild type showed no neutralizing activity towards E79. EDTA and sodium deoxycholate were demonstrated to abolish the neutralizing capacity of the smooth LPS. One E79 receptor site was shown to be equivalent to 10(-16) g of LPS.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference37 articles.
1. Adams M. H. 1959. Bacteriophages. Interscience Publishers Inc. New York.
2. Interaction of Pseudomonas bacteriophage 2 with the slime polysaccharide and lipopolysaccharide ofPseudomonas aeruginosa strain BI;Bartell P. F.;J. Virol.,1971
3. Isolement de substances receptrices des bacteriophages chez les;Beumer J.;Shigellae. Ann. Inst. Pasteur Paris.,1960
4. Blocking of bacteriophages 4W and >5 with lipopolysaccharides from Escherichia coli K-12 mutants;Boman H. G.;J. Bacteriol.,1975
5. The fluorescent staining of bacteriophage nucleic acids;Bradley D. E.;J. Gen. Microbiol.,1955
Cited by
43 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献