Epstein-Barr virus transformation of human B lymphocytes despite inhibition of viral polymerase-Reference-Cited by-同舟云学术

Epstein-Barr virus transformation of human B lymphocytes despite inhibition of viral polymerase

Published:1985-01 Issue:1 Volume:53 Page:299-301
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Sixbey J W,Pagano J S

Abstract

Epstein-Barr virus transformed human lymphocytes despite the presence of up to 500 microM acyclovir [9-(2-hydroxyethoxymethyl)guanine], a viral DNA polymerase inhibitor. The transformed cells contained multiple Epstein-Barr virus genome copy numbers. Functional viral DNA polymerase is probably not required for cell transformation and the initial amplification of the viral genome.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.53.1.299-301.1985

Reference21 articles.

1. Copy number and location of Epstein-Barr viral genomes in neonatal human Iymphocytes transformed after separation by size and treatment with mitogens;Anvret M.;Virology,1981

2. isolation of mononuclear cells and granulocytes from human blood;Boyum A.;Scand. J. Clin. Lab. Invest. Suppl.,1968

3. Phosphorylation of acyclovir [9-(2-hydroxyethoxymethyl)guanine] in Epstein-Barr virus-infected Iymphoblastoid cell lines;Colby B. M.;J. Virol.,1981

4. Effect of acyclovir [9-(2-hydroxyethoxymethyl)guanine] on Epstein-Barr virus DNA replication;Colby B. M.;J. Virol.,1980

5. Acyclovir inhibition of Epstein-Barr virus replication;Datta A. K.;Proc. Natl. Acad. Sci. U.S.A.,1980

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pathogenesis of Epstein-Barr Virus;Human Tumor Viruses;2014-04-09

2. Contrasting effects of hydroxyurea on cell growth and reduction in Epstein-Barr virus genomes in EBV-infected epithelioid cell lines vs. Burkitt's lymphoma cell lines;Journal of Medical Virology;2003-06

3. Pathogenic roles for Epstein–Barr virus (EBV) gene products in EBV-associated proliferative disorders;Critical Reviews in Oncology/Hematology;2003-01

4. Prevention and treatment of epstein-barr virus-associated lymphoproliferative disorders in recipients of bone marrow and solid organ transplants;British Journal of Haematology;2002-11-18

5. The antiviral prophylaxis of post-transplant lymphoproliferative disorder;Springer Seminars in Immunopathology;1998-09