Cyanide Resistance in Achromobacter II. Mechanism of Cyanide Resistance

Author:

Oka Tetuo1,Arima Kei1

Affiliation:

1. Laboratory of Fermentation, Department of Agricultural Chemistry, University of Tokyo, Tokyo, Japan

Abstract

Oka, Tetuo (University of Tokyo, Tokyo, Japan), and Kei Arima . Cyanide resistance in Achromobacter . II. Mechanism of cyanide resistance. J. Bacteriol. 90: 744–747. 1965.—Photochemical data showed that the only oxidase found in the cyanide-sensitive cells of Achromobacter was cytochrome o , and that cyanide-resistant cells contained at least two oxidases. The oxidase responsible for cyanide resistance was a pigment the CO compound of which had its absorption band at a wavelength longer than 580 mμ. In addition, kinetic data suggested that there were two oxidases having different affinities for cyanide. From the data presented, resistance to cyanide in Achromobacter strain D was attributed to the induced formation of cytochrome a 2 , which has a very low affinity for cyanide. Several characteristics of cytochrome a 2 as a cytochrome oxidase are summarized.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference9 articles.

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2. Cyanide resistance in Achromobacter. I. Induced formation of cytochrome a2 and its role in cyanide-resistant respiration;ARIMA K.;J. Bacteriol.,1965

3. Photochemical action spectra of carbon monoxide-inhibited respiration;CASTOR L.;J. Biol. Chem. 217:.453-465.,1955

4. Photochemical determinations of the oxidase of bacteria;CASTOR L.;J. Biol. Chem.,1959

5. Cytochromes of group A and their prosthetic groups;LEMBERG R.;Advan. Enzymol.,1961

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