Abstract
Peritoneal exudate cells from immunized mice inhibit the intracellular growth of Histoplasma capsulatum. The lymphocyte is the mediator cell of this phenomenon. Lymphocytes from immunized animals are highly activated cells. Supernatants from cultures of immune lymphocytes or from cultures of mitogen-stimulated lymphocytes did not arm macrophages from normal animals to inhibit the intracellular growth of H. capsulatum.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference36 articles.
1. The activation of mononuclear phagocytes in vitro: immunologically mediated enhancement;Adams O.;J. Reticuloendothel. Soc.,1973
2. Cellular recognition by mouse Iymphocytes in vitro. I. Definition of a new technique and results of stimulation by phytohemagglutinin and specific antigens;Adler W. H.;J. Exp. Med.,1970
3. Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages;Bast R. C.;Cell. Immunol.,1974
4. Inhibition of multiplication of Toxoplasma gondii by human monocytes exposed to T-lymphocyte products;Borges J. S.;J. Exp. Med.,1975
5. Macrophage activation by Iymphocyte mediators;David J. R.;Fed. Proc.,1975