Abstract
One hundred strains of Staphylococcus epidermidis were tested by the double-disk agar diffusion method for their susceptibility to cephalothin, to sulfamethoxazole-trimethoprim, and to combinations of these drugs. Forty-five strains showed a bridging inhibition zone between the two disks, suggesting a synergistic effect of the combination of cephalothin plus sulfamethoxozole-trimethoprim against these strains. Ten of these strains were retested against the individual drugs and their combination by the twofold broth dilution method. No strain showed higher susceptibility to any combination as compared with cephalothin alone.
Publisher
American Society for Microbiology
Reference14 articles.
1. Antimicrobial susceptibility and selection of resistance among Staphylococcus epidermidis isolates recovered from patients with infections of indwelling foreign devices;Archer G. L.;Antimicrob. Agents Chemother.,1978
2. Atkinson B. 1977. A sample of bacterial isolates in the U.S. and their susceptibility to antimicrobial agents p. 235-256. In V. Lorian (ed.) Significance of medical microbiology in the care of patients. The Williams & Wilkins Co. Baltimore.
3. Antibiotic susceptibility testing by a standardized single disc method;Bauer A. W.;Am. J. Clin. Pathol.,1966
4. Busby S. R. M. 1973. Trimethoprim-sulfamethoxazole in vitro microbiological aspects p. 10-30. In M. Finland and E. H. Kass (ed.) Trimethoprim-sulfamethoxazole in microbiological pharmacological and clinical considerations. The University of Chicago Press Chicago.
5. Prosthetic valve endocarditis: analysis of 38 cases;Dismukes W. E.;Circulation,1973
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