Consumption Patterns and In Vitro Resistance of Streptococcus pneumoniae to Fluoroquinolones

Abstract

ABSTRACTThis article analyzes patterns of consumption of fluoroquinolones and documents thein vitroresistances ofStreptococcus pneumoniaeisolates to fluoroquinolones in the ambulatory care setting in Belgium over time. The volume of fluoroquinolone consumption has fallen consistently since 2003. Fluoroquinolones were used primarily for their registered indications (i.e., urinary tract infections and lower respiratory tract infections). The MIC distributions of moxifloxacin and levofloxacin inS. pneumoniaeisolates remained stable during 2004 to 2009, and the level of resistance to moxifloxacin and levofloxacin was low (≤1%).