Regulation of the multiple antibiotic resistance (mar) regulon by marORA sequences in Escherichia coli-Reference-Cited by-同舟云学术

Regulation of the multiple antibiotic resistance (mar) regulon by marORA sequences in Escherichia coli

Published:1995-07 Issue:14 Volume:177 Page:4176-4178
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Martin R G¹,Nyantakyi P S¹,Rosner J L¹

Affiliation:

1. Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892-0560, USA.

Abstract

The mar operon and adjacent sequences were subcloned on a low-copy-number plasmid to identify essential regulatory elements. A 1.1-kbp fragment containing 133 bp of the operator-promoter region (marO), the full marRA gene sequences, and only 10 of 72 marB codons provided a dela mar strain with normal repressibility and inducibility and the ability to beget mar constitutive mutants.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.177.14.4176-4178.1995

Reference17 articles.

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2. Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli;Cohen S. P.;J. Bacteriol.,1993

3. Salicylate induction of antibiotic resistance in Escherichia coli: activation of the mar operon and a mar-independent pathway;Cohen S. P.;J. Bacteriol.,1993

4. marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli;Cohen S. P.;J. Bacteriol.,1988

5. Overexpression of the MarA positive regulator is sufficient to confer multiple antibiotic resistance in Escherichia coli;Gambino L.;J. Bacteriol.,1993

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