Comparison of Assessment of Oxygen Consumption, Etest, and CLSI M38-A2 Broth Microdilution Methods for Evaluation of the Susceptibility of Aspergillus fumigatus to Posaconazole-Reference-Cited by-同舟云学术

Comparison of Assessment of Oxygen Consumption, Etest, and CLSI M38-A2 Broth Microdilution Methods for Evaluation of the Susceptibility of Aspergillus fumigatus to Posaconazole

Published:2009-11 Issue:11 Volume:53 Page:4921-4923
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Araujo Ricardo¹²,Espinel-Ingroff Ana³

Affiliation:

1. IPATIMUP, Institute of Pathology and Molecular Immunology, University of Porto, Porto, Portugal

2. Department of Microbiology, Faculty of Medicine, University of Porto, Porto, Portugal

3. Virginia Commonwealth University Medical Center, Richmond, Virginia

Abstract

ABSTRACT Posaconazole MICs for 50 Aspergillus fumigatus isolates with distinct genotypes were determined by three methods. MICs were ≥0.5 μg/ml for 5, 11, and 15 strains by the CLSI reference M38-A2, Etest (48-h), and oxygen consumption methods, respectively. The levels of categorical agreement between the results obtained by the CLSI method and those obtained by the oxygen consumption and Etest methods were 80 and 84%, respectively.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00862-09

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