Serological analysis of dermatophyte isolates with monoclonal antibodies produced against Microsporum canis-Reference-Cited by-同舟云学术

Serological analysis of dermatophyte isolates with monoclonal antibodies produced against Microsporum canis

Published:1985-01 Issue:1 Volume:21 Page:138-139
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Polonelli L,Morace G

Abstract

Hybridoma cells produced by fusing myeloma cells with spleen cells from mice immunized with a soluble antigen of Microsporum canis yielded 30 antibody-producing clones. Six of these clones, propagated as ascites tumors in mice, showed two different types of monoclonal antibodies. The type 1 monoclonal antibody reacted with 17 heterologous and 10 homologous dermatophyte antigens. Type 2 monoclonal antibodies were unable to precipitate three antigens from different isolates of M. canis, thus suggesting the occurrence of different serotypes within the species.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.21.1.138-139.1985

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