Aging and the Immune Response to Tetanus Toxoid: Diminished Frequency and Level of Cellular Immune Reactivity to Antigenic Stimulation-Reference-Cited by-同舟云学术

Aging and the Immune Response to Tetanus Toxoid: Diminished Frequency and Level of Cellular Immune Reactivity to Antigenic Stimulation

Published:1998-11 Issue:6 Volume:5 Page:894-896
ISSN:1071-412X
Container-title:Clinical Diagnostic Laboratory Immunology
language:en
Short-container-title:Clin Diagn Lab Immunol

Author:

Schatz Desmond¹,Ellis Tamir²,Ottendorfer Eric²,Jodoin Eric²,Barrett Douglas¹,Atkinson Mark²

Affiliation:

1. Departments of Pediatrics1 and

2. Pathology,2 University of Florida, Gainesville, Florida

Abstract

ABSTRACT The period of efficacious immune reactivity afforded by tetanus immunization and the need for continuing some forms of tetanus vaccination programs have been the subjects of recent debates. Our studies demonstrate that the level of antitetanus immunity based on immunological memory (i.e., cellular immune responsiveness) varies dramatically as a function of age, with older individuals constituting a population which is increasingly susceptible to tetanus infection.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.5.6.894-896.1998

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