Adenovirus hexon monoclonal antibody that is group specific and potentially useful as a diagnostic reagent

Author:

Cepko C L,Whetstone C A,Sharp P A

Abstract

A monoclonal antibody to the adenovirus 2 hexon protein was produced and characterized as a group-specific antibody. Positive reactivity in immunoprecipitation, indirect immunofluorescence, and radioimmunoassays was observed with human, canine, swine, bovine, murine, and simian adenoviruses. This monoclonal antibody should provide a specific and sensitive diagnostic reagent for detection of all mammalian adenoviruses.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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