Reduction of malachite green to leucomalachite green by intestinal bacteria

Author:

Henderson A L1,Schmitt T C1,Heinze T M1,Cerniglia C E1

Affiliation:

1. National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA.

Abstract

Intestinal microfloras from human, rat, mouse, and monkey fecal samples and 14 pure cultures of anaerobic bacteria representative of those found in the human gastrointestinal tract metabolized the triphenylmethane dye malachite green to leucomalachite green. The reduction of malachite green to the leuco derivative suggests that intestinal microflora could play an important role in the metabolic activation of the triphenylmethane dye to a potential carcinogen.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference22 articles.

1. Malachite green: a review;Alderman D. J.;J. Fish Dis.,1985

2. Malachite green: a pharmacokinetic study in rainbow trout, Oncorhynchus mykiss (Walbaum);Alderman D. J.;J. Fish Dis.,1993

3. Fate and distribution of some drugs used in aquaculture;Allen J. L.;Vet. Hum. Toxicol.,1986

4. Determination of malachite green residues in the eggs, fry, and adult muscle tissue of rainbow trout (Oncorhynchus mykiss);Allen J. L.;J. Assoc. Off. Anal. Chem. Int.,1994

5. Role of gastrointestinal mucosa and microflora in the bioactivation of dietary and environmental mutagens or carcinogens;Chadwick R. W.;Drug Metab. Rev.,1992

Cited by 82 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Degradation and decolorization of textile azo dyes by effective fungal-bacterial consortium;Molecular Biology Reports;2023-09-12

2. Dynamics of the role of LacMeta laccase in the complete degradation and detoxification of malachite green;World Journal of Microbiology and Biotechnology;2023-03-21

3. Malachite green and leucomalachite green in fish: a global systematic review and meta-analysis;Environmental Science and Pollution Research;2023-03-15

4. Purification and characterization of laccase from Ganoderma lucidum and its application in decolorization of malachite green dye;Bioresource Technology Reports;2023-02

5. A review: On malachite green; synthesis, uses and toxic effects;INTERNATIONAL CONFERENCE ON HUMANS AND TECHNOLOGY: A HOLISTIC AND SYMBIOTIC APPROACH TO SUSTAINABLE DEVELOPMENT: ICHT 2022;2023

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3