Opsonophagocytosis of Chlamydia pneumoniae by Human Monocytes and Neutrophils

Author:

Lausen Mads1ORCID,Pedersen Mathilde Selmar1,Rahman Nareen Sherzad Kader1,Holm-Nielsen Liv Therese1,Farah Faduma Yahya Mohamed1,Christiansen Gunna12,Birkelund Svend1

Affiliation:

1. Department of Health Science and Technology, Aalborg University, Aalborg, Denmark

2. Department of Biomedicine, Aarhus University, Aarhus, Denmark

Abstract

The human respiratory tract pathogen Chlamydia pneumoniae , which causes mild to severe infections, has been associated with the development of chronic inflammatory diseases. To understand the biology of C. pneumoniae infections, several studies have investigated the interaction between C. pneumoniae and professional phagocytes. However, these studies have been conducted under nonopsonizing conditions, making the role of opsonization in C. pneumoniae infections elusive.

Funder

Joint Strategic Research Programme on Fighting Antibiotic Resistance

Aase og Ejnar Danielsens Fond

Det Obelske Familiefond

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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