Bacteriophage Resistance Alters Antibiotic-Mediated Intestinal Expansion of Enterococci-Reference-Cited by-同舟云学术

Bacteriophage Resistance Alters Antibiotic-Mediated Intestinal Expansion of Enterococci

Published:2019-06 Issue:6 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Chatterjee Anushila¹,Johnson Cydney N.¹,Luong Phat¹,Hullahalli Karthik²,McBride Sara W.¹,Schubert Alyxandria M.³,Palmer Kelli L.²^ORCID,Carlson Paul E.³,Duerkop Breck A.¹^ORCID

Affiliation:

1. Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA

2. Department of Biological Sciences, University of Texas at Dallas, Richardson, Texas, USA

3. Division of Bacterial, Parasitic, and Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluations and Research, Food and Drug Administration, Silver Spring, Maryland, USA

Abstract

Enterococcus faecalis is a human intestinal pathobiont with intrinsic and acquired resistance to many antibiotics, including vancomycin. Nature provides a diverse and virtually untapped repertoire of bacterial viruses, or bacteriophages (phages), that could be harnessed to combat multidrug-resistant enterococcal infections.

Funder

National Institutes of Health and Food and Drug Administration

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00085-19

Reference47 articles.

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5. Vancomycin-Resistant Enterococci: Colonization, Infection, Detection, and Treatment

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