Affiliation:
1. Servicio de Microbiologı́a, Hospital Ramón y Cajal, 28034 Madrid, Spain
Abstract
ABSTRACT
A clinical strain of
Acinetobacter baumannii
(strain Ab RYC 52763/97) that was isolated during an outbreak in our hospital and that was resistant to all β-lactam antibiotics tested produced three β-lactamases: a TEM-1-type (pI, 5.4) plasmid-mediated β-lactamase, a chromosomally mediated OXA-derived (pI, 9.0) β-lactamase, and a presumptive chromosomal cephalosporinase (pI, 9.4). The nucleotide sequence of the chromosomal cephalosporinase gene shows for the first time the gene encoding an AmpC β-lactamase in
A. baumannii
. In addition, we report here the biochemical properties of this
A. baumannii
AmpC β-lactamase.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
154 articles.
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