Synergistic Interactions between Mammalian Antimicrobial Defense Peptides

Author:

Yan Hong1,Hancock Robert E. W.1

Affiliation:

1. Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3

Abstract

ABSTRACT A single animal can express several cationic antimicrobial peptides with different sequences and structures. We demonstrate that mammalian peptides from different structural classes frequently show synergy with each other and selectively show synergy with human lysozyme.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference15 articles.

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4. The role of antimicrobial peptides in animal defenses.;Hancock R. E. W.;Proc. Natl. Acad. Sci. USA,2000

5. Cationic peptides: a new source of antibiotics.;Hancock R. E. W.;Trends Biotechnol.,1998

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