Thalidomide Inhibits Granulocyte Responses in Healthy Humans after Ex Vivo Stimulation with Bacterial Antigens-Reference-Cited by-同舟云学术

Thalidomide Inhibits Granulocyte Responses in Healthy Humans after Ex Vivo Stimulation with Bacterial Antigens

Published:2001-05 Issue:5 Volume:45 Page:1547-1549
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Juffermans Nicole P.¹²,Verbon Annelies¹²,Schultz Marc J.¹²,Hack C. Erik³⁴,van Deventer Sander J. H.¹,Speelman Peter²,van der Poll Tom¹²

Affiliation:

1. Laboratory of Experimental Internal Medicine,1

2. Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS,2 and

3. Laboratory for Experimental and Clinical Immunology,3 Academic Medical Center, University of Amsterdam, and

4. the Laboratory of Pathophysiology of Plasma Proteins, Central Laboratory of The Netherlands Red Cross Blood Transfusion Service,4 Amsterdam, The Netherlands

Abstract

ABSTRACT Ingestion of thalidomide was associated with a reduction in the upregulation of the granulocyte activation marker CD11b and a reduced capacity to release elastase and lactoferrin after stimulation with lipopolysaccharide or lipoteichoic acid. A single oral dose of thalidomide attenuates neutrophil activation upon ex vivo stimulation with bacterial antigens.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.5.1547-1549.2001

Reference14 articles.

1. Lactoferrin turnover in man.;Bennett R. M.;Clin. Sci.,1979

2. Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors.;Bouma M. G.;J. Immunol.,1997

3. Effects of thalidomide on neutrophil respiratory burst, chemotaxis, and transmigration of cytokine- and endotoxin-activated endothelium.;Dunzendorfer S.;Naunyn-Schmiederberg's Arch. Pharmacol.,1997

4. Role of cytokines in rheumatoid arthritis.;Feldmann M.;Annu. Rev. Immunol.,1996

5. Leukocyte traffic in the lung.;Hogg J. C.;Annu. Rev. Physiol.,1995

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