Cultured Renal Proximal Tubular Epithelial Cells Resemble a Stressed/Damaged Kidney While Supporting BK Virus Infection-Reference-Cited by-同舟云学术

Cultured Renal Proximal Tubular Epithelial Cells Resemble a Stressed/Damaged Kidney While Supporting BK Virus Infection

Published:2023-05-31 Issue:5 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

An Ping¹,Sáenz Robles Maria Teresa¹,Cantalupo Paul G.²,Naik Abhijit S.³,Sealfon Rachel⁴,Imperiale Michael J.⁵,Pipas James M.¹^ORCID

Affiliation:

1. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

2. Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

3. Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

4. Flatiron Institute, New York, New York, USA

5. Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

Abstract

Cultured primary human cells provide powerful tools for the study of viral infectious cycles and host virus interactions. In the case of BKV-associated nephropathy, viral replication occurs primarily in the proximal tubule epithelia in the kidney.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00343-23

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