Let It Go: HIV-1 cis -Acting Repressive Sequences

Author:

Ostermann Philipp Niklas1,Ritchie Anastasia1,Ptok Johannes1,Schaal Heiner1ORCID

Affiliation:

1. Institute of Virology, University Hospital Düsseldorf, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Abstract

After human immunodeficiency virus type 1 (HIV-1) was identified in the early 1980s, intensive work began to understand the molecular basis of HIV-1 gene expression. Subgenomic HIV-1 RNA regions, spread throughout the viral genome, were described to have a negative impact on the nuclear export of some viral transcripts.

Funder

Stiftung für AIDS-Forschung, Düsseldorf

Forschungskommission der Heinrich-Heine-Universität Düsseldorf

Jürgen Manchot Stiftung

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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