In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188-Reference-Cited by-同舟云学术

In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188

Published:2000-08 Issue:8 Volume:44 Page:2190-2192
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Espuelas S.¹,Legrand P.²,Loiseau P. M.³,Bories C.³,Barratt G.²,Irache J. M.¹

Affiliation:

1. Departamento de Farmacia y Tecnologı́a Farmacéutica, Facultad de Farmacia, Universidad de Navarra, 31080 Pamplona, Spain,1 and

2. UMR 86, Faculté de Pharmacie, UniversitéParis-Sud,2 and

3. Biologie et Contrôle des Organismes Parasites, UPRES-EA 398, Faculté de Pharmacie, Université de Paris-Sud,392296 Châtenay-Malabry, France

Abstract

ABSTRACT A micellar formulation of amphotericin B (AmB) solubilized with poloxamer 188 was evaluated against an AmB Leishmania donovani -resistant line. A concave isobologram showed a synergistic effect of this association against promastigotes. This result was confirmed with amastigotes since the 50% effective concentration of the new formulation was 100 times less than that of the control AmB formulation.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.44.8.2190-2192.2000

Reference24 articles.

1. Drug-loaded nanoparticles—preparation methods and drug targeting issues.;Alléman E.;Eur. J. Pharm. Biopharm.,1993

2. Nonionic block copolymers potentiate activities of drugs for treatment of infections with Toxoplasma gondii

3. Human leishmaniasis: clinical, diagnostic and chemotherapic developments in the last 10 years.;Berman J.;Clin. Infect Dis.,1997

4. Treatment of visceral leishmaniasis with amphotericin B colloidal dispersion.;Berman J.;Chemotherapy (Basel),1999

5. Efficacy and safety of liposomal amphotericin B (AmBisome) for visceral leishmaniasis in endemic developing countries.;Berman J. D.;Bull. W. H. O.,1998

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