Affiliation:
1. Cambridge BioScience Corporation, Worcester, Massachusetts 01605.
Abstract
Recombinant human immunodeficiency virus (HIV) env antigen was attached to polystyrene particles, and these complexes were used to develop the first latex agglutination assay for antibodies to HIV. A total of 95 positive and 116 negative human serum samples were assayed for antibodies to HIV by latex agglutination, and results were compared with those of a commercial enzyme immunoassay. Latex agglutination was also compared with, and found to be completely concordant with, Western blot (immunoblot) analysis with virion antigens.
Publisher
American Society for Microbiology
Reference6 articles.
1. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS);Barre-Sinoussi F.;Science,1983
2. Diagnosis of human immunodeficiency virus infection by immunoassay using a molecularly cloned and expressed virus envelope polypeptide;Burke D. S.;Ann. Intern. Med.,1987
3. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS;Gallo R. C.;Science,1984
4. Gallo R. C. S. Z. Salahuddin M. Popovic G. M. Shearer M. Kaplan B. F. Haynes T. J. Palker R. Redfield J. Oleske B. Safai G. White P. Foster and P. D. Markham.
1984. Latex particle
5. 1+ 2+ 3+ Latex Agglutination Reaction 4+ assays in laboratory medicine. Il. Lab. Manage. 22:26-35.
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