Affiliation:
1. Department of Microbiology, Tel Aviv University, Tel Aviv, Israel
Abstract
The experiments presented in this paper support earlier evidence that ribosomes are released from polysomes when they encounter a codon for which no charged transfer ribonucleic acid is available. However, it is further shown that these ribosomes then reinitiate and resume translation. The size and the level of polysomes during deprival of an amino acid is a function of the frequency with which that particular amino acid appears in cellular proteins. Polysomes from starved cells are more stable than those from growing cells, and, moreover, polysomes from starved relaxed strains are more stable than those from starved stringent strains.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference15 articles.
1. Nucleic acid metabolism in relation to the Iysogenic phenomenon;Borek E.;J. Bacteriol.,1955
2. Mutants of Escherichia coli requiring methionine or vitamin B,2;Davis B. D.;J. Bacteriol.,1950
3. A study of the relationship between polyribosomes and messenger RNA in Escherichia coli;Friesen J. D.;J. Mol. Biol.,1968
4. FormylmethionyltRNA dependence of amino acid incorporation in extracts of trimethoprim treated Escherichia coli;Eisenstadt J.;Science,1966
5. Messenger RNA. Annu;Geiduschek P.;Rev. Biochem.,1969
Cited by
35 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献