Role of IS Kpn23 in bla BKC-1 Expression and Mobilization

Author:

Martins Willames M. B. S.1ORCID,Nascimento Ezequiel A.1,Cayô Rodrigo12,Gales Ana C.1

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

2. Laboratório de Imunologia e Bacteriologia, Setor de Biologia Molecular, Microbiologia e Imunologia, Departamento de Ciências Biológicas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, Brazil

Abstract

This study aimed to verify the role of IS Kpn23 in the expression and mobilization of bla BKC-1 and aph(3′)-VIi . Five constructs related to the natural bla BKC-1 genetic background in plasmid p60136 were made and submitted for antimicrobial susceptibility testing and quantitative reverse transcription-PCR.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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