A Cell Culture-Adapted Vaccine Virus against the Current African Swine Fever Virus Pandemic Strain-Reference-Cited by-同舟云学术

A Cell Culture-Adapted Vaccine Virus against the Current African Swine Fever Virus Pandemic Strain

Published:2021-06-24 Issue:14 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Borca M. V.¹,Rai A.¹²,Ramirez-Medina E.¹³,Silva E.¹⁴,Velazquez-Salinas L.¹⁴,Vuono E.¹⁵,Pruitt S.¹,Espinoza N.¹,Gladue D. P.¹^ORCID

Affiliation:

1. Plum Island Animal Disease Center, ARS, USDA, Greenport, New York, USA

2. Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, Tennessee, USA

3. Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Mansfield, Connecticut, USA

4. Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, USA

5. Department of Pathobiology and Population Medicine, Mississippi State University, Mississippi State, Mississippi, USA

Abstract

African swine fever is currently causing a pandemic resulting in devastating losses to the swine industry. Experimental ASF vaccines rely on the production of vaccine in primary swine macrophages, which are difficult to use for the production of a vaccine on a commercial level.

Funder

U.S. Department of Homeland Security

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00123-21

Reference27 articles.

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3. African Swine Fever Virus Georgia Isolate Harboring Deletions of MGF360 and MGF505 Genes Is Attenuated in Swine and Confers Protection against Challenge with Virulent Parental Virus