Elucidation of the Interleukin 12 Production Mechanism during Intracellular Bacterial Infection in Amberjack, Seriola dumerili

Author:

Matsumoto Megumi1,Kubota Taisei2,Fujita Sinsuke2,Shiozaki Kazuhiro12,Kishida Shosei3,Yamamoto Atsushi12

Affiliation:

1. The United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima, Japan

2. Faculty of Fisheries, Kagoshima University, Kagoshima, Japan

3. Faculty of Medicine, Kagoshima University, Kagoshima, Japan

Abstract

Intracellular bacterial infections affect all vertebrates. Cultured fish are particularly vulnerable because no effective protection measures have been established since such infections emerged approximately 50 years ago. As in other vertebrates, the induction of cell-mediated immunity (CMI) plays an important role in protecting fish against infection. However, details of the mechanism of CMI induction in fish have not been clarified.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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