Author:
Skóra Magdalena,Bulanda Małgorzata,Jagielski Tomasz
Abstract
ABSTRACTThein vitroactivities of 11 antifungal drugs against 68ScopulariopsisandMicroascusstrains were investigated. Amphotericin B, 5-fluorocytosine, fluconazole, itraconazole, ketoconazole, miconazole, posaconazole, voriconazole, and ciclopirox showed no or poor antifungal effect. The best activities were exhibited by terbinafine and caspofungin, where the MIC and MEC (minimal effective concentration) ranges were 0.0313 to >16 μg/ml and 0.125 to 16 μg/ml, respectively. The MIC and MEC modes were both 1 µg/ml for terbinafine and caspofungin; the MIC50and MEC50were 1 µg/ml for both drugs, whereas the MIC90and MEC90were 4 µg/ml and 16 µg/ml, respectively.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference27 articles.
1. Corneal ulcer with Scopulariopsis brevicaulis and Staphylococcus aureus–a rare case report;J Indian Med Assoc,2012
2. Sinusitis caused by Scopulariopsis brevicaulis: case report and review of the literature;Med Mycol Case Rep,2014
3. Fatal bronchial invasion of Scopulariopsis brevicaulis in an acute monocytic leukemia patient;Diagn Microbiol Infect Dis,2012
4. Scopulariopsis brevicaulis infection of prosthetic valve resembling aspergilloma on histopathology;Cardiovasc Pathol,2011
5. Scopulariopsis associated meningitis in adult Nigerian AIDS patient–a case report;West Afr J Med,2003
Cited by
15 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献