Increasing Incidence of Candidemia: Results from a 20-Year Nationwide Study in Iceland

Author:

Ásmundsdóttir Lena Rós1,Erlendsdóttir Helga2,Gottfredsson Magnús123

Affiliation:

1. University of Iceland, Reykjavik 101Departments of

2. Clinical Microbiology

3. Internal Medicine, Landspitali University Hospital, Reykjavik 108, Iceland

Abstract

ABSTRACT A nationwide study on candidemia was conducted in Iceland from 1980 to 1999. The annual incidence increased from 1.4 cases/100,000 inhabitants/year between 1980 and 1984 to 4.9 cases/100,000 inhabitants/year between 1995 and 1999 ( P < 0.0001). Candidemia episodes at university hospitals increased from 0.15/1,000 admissions to 0.55/1,000 admissions ( P < 0.0001). Candida albicans was the predominant species responsible (64.4%). The national import of fluconazole increased approximately fourfold during the second half of the study, but increased resistance to this agent was not observed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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