In Vitro Antifungal Resistance of Candida auris Isolates from Bloodstream Infections, South Africa

Author:

Maphanga Tsidiso G.1ORCID,Naicker Serisha D.12,Kwenda Stanford3,Muñoz Jose F.4ORCID,van Schalkwyk Erika1,Wadula Jeannette5,Nana Trusha6,Ismail Arshad3ORCID,Coetzee Jennifer7,Govind Chetna8,Mtshali Phillip S.3,Mpembe Ruth S.1,Govender Nelesh P.129ORCID

Affiliation:

1. National Institute for Communicable Diseases, Centre for Healthcare-Associated Infections, Antimicrobial Resistance, and Mycoses, National Health Laboratory Service, Johannesburg, South Africa

2. School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

3. National Institute for Communicable Diseases, Sequencing Core Facility, National Health Laboratory Service, Johannesburg, South Africa

4. Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA

5. National Health Laboratory Service, Chris Hani Baragwaneth Academic Hospital, Soweto, South Africa

6. National Health Laboratory Service, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

7. AMPATH National Laboratory Service, Centurion, South Africa

8. Lancet Laboratories, Durban, South Africa

9. Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

Abstract

Candida auris is a multidrug-resistant fungal pathogen that is endemic in South African hospitals. We tested bloodstream C. auris isolates that were submitted to a reference laboratory for national laboratory-based surveillance for candidemia in 2016 and 2017.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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