Assessment of Neutrophil Function in Patients with Septic Shock: Comparison of Methods

Author:

Wenisch C.12,Fladerer P.2,Patruta S.1,Krause R.2,Hörl W.3

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine I,1 and

2. Division of Infectious Diseases, Department of Medicine, University Hospital of Graz, Graz,2 Austria

3. Division of Nephrology, Department of Internal Medicine III,3 University Hospital of Vienna, Vienna, and

Abstract

ABSTRACT Patients with septic shock are shown to have decreased neutrophil phagocytic function by multiple assays, and their assessment by whole-blood assays (fluorescence-activated cell sorter analysis) correlates with assays requiring isolated neutrophils (microscopic and spectrophotometric assays). For patients with similar underlying conditions but without septic shock, this correlation does not occur.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference25 articles.

1. Impaired phagocytosis in patients. Studies on mechanisms.;Alexiewicz J. M.;Am. J. Nephrol.,1991

2. The association of impaired neutrophil chemotaxis with postoperative surgical sepsis.;Duignan J. P.;Br. J. Surg.,1986

3. Increased expression of C3b receptors on polymorphonuclear leukocytes induced by chemotactic factors and purification procedures.;Fearon D. T.;J. Immunol.,1983

4. The effect of various cell separation procedures on assays of neutrophil function.;Glasser L.;Am. J. Clin. Pathol.,1990

5. Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.;Goldstein I. M.;J. Clin. Investig.,1975

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3