Disparate Candida albicans Biofilm Formation in Clinical Lipid Emulsions Due to Capric Acid-Mediated Inhibition-Reference-Cited by-同舟云学术

Disparate Candida albicans Biofilm Formation in Clinical Lipid Emulsions Due to Capric Acid-Mediated Inhibition

Published:2019-11 Issue:11 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Willems Hubertine M. E.¹,Stultz Jeremy S.¹,Coltrane Molly E.²,Fortwendel Jabez P.³,Peters Brian M.¹⁴

Affiliation:

1. Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA

2. College of Pharmacy, The University of Tennessee Health Science Center, Memphis, Tennessee, USA

3. University of Tennessee, Knoxville, Tennessee, USA

4. Department of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA

Abstract

Receipt of parenteral nutrition (PN) remains an independent risk factor for developing catheter-related bloodstream infections (CR-BSI) caused by fungi, including by the polymorphic fungus Candida albicans , which is notoriously adept at forming drug-resistant biofilm structures. Among a variety of macronutrients, PN solutions contain lipid emulsions to supply daily essential fats and are often delivered via central venous catheters (CVCs).

Funder

UT | Health Science Center, University of Tennessee

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01394-19

Reference71 articles.

1. Long-term total parenteral nutrition with growth, development, and positive nitrogen balance. 1968;Dudrick SJ;Nutr Hosp,2001

2. SMOFlipid Protects Preterm Neonates against Perinatal Nutrition–Associated Cholestasis

3. Effects of pH and osmolality on phlebitic potential of infusion solutions for peripheral parenteral nutrition.