Immunochemistry of the Capsular Polysaccharides from Clostridium perfringens: Selected Hobbs Strains 1, 5, 9, and 10

Author:

Cherniak Robert1,Henderson Bernice G.1

Affiliation:

1. Departments of Chemistry and Biology, Georgia State University, Atlanta, Georgia 30303

Abstract

The properties of the immunochemically distinct substances isolated from four strains of Clostridium perfringens , mucoid variants of Hobbs 1, 5, 9, and 10, were shown to be compatible with the hypothesis that polysaccharides are generally responsible for the “type-specificity” of these organisms. The presence of “group-specific” substance was demonstrated by the cross-reaction of recent preparations of Hobbs 5 antisera with the isolated polysaccharides. The cross-reactions were not observed with specific antisera of the other strains studied and were independent of the “type-specific” phenomenon.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference8 articles.

1. Capsular polysaccharides of Clostridium perfringens Hobbs 5;Baine H.;Biochemistry,1971

2. Elimination of host tissue reactions in immunodiffusion and immunoelectrophoretic studies of arboviruses (33655);Ibrahim A. N.;Proc. Soc. Exp. Biol. Med.,1969

3. Kabat E. A. Experimental immunochemistry. 1961. Charles C Thomas Publisher Springfield Ill.

4. The polysaccharides of Clostridium perfringens;Meisel-Mikolajczyk F.;Arch. Immunol. Ther. Exp.,1963

5. Immunochemical investigations on the antigenic structure of heat resistant "Cl. perfringens;Meisel-Mikolajczyk F.;Progr. Immunobiol. Stand.,1970

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