Mild or Malign: Clinical Characteristics and Outcomes of Clostridium difficile Infection in Thailand-Reference-Cited by-同舟云学术

Mild or Malign: Clinical Characteristics and Outcomes of Clostridium difficile Infection in Thailand

Published:2020-08-24 Issue:9 Volume:58 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Imwattana Korakrit¹²^ORCID,Putsathit Papanin³^ORCID,Leepattarakit Teera²^ORCID,Kiratisin Pattarachai²,Riley Thomas V.¹³⁴⁵^ORCID

Affiliation:

1. School of Biomedical Sciences, The University of Western Australia, Crawley, Western Australia, Australia

2. Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

3. School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia

4. School of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia

5. Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia

Abstract

Little is known about the clinical characteristics of Clostridium difficile infection (CDI) in Asia in general, and Thailand specifically, with a few studies suggesting that the disease may be milder than elsewhere. This study aimed to describe CDI in Thailand, evaluate treatment options and their outcomes, and explore possible protective factors responsible for any unique disease characteristics. From 2015 to 2018, 469 patients were included in the study. All patients had their stools tested for the tcdB gene by direct PCR and detection of toxigenic C. difficile by culture.

Funder

Mahidol University

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01217-20

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