Lytic Bacteriophages Facilitate Antibiotic Sensitization of Enterococcus faecium-Reference-Cited by-同舟云学术

Lytic Bacteriophages Facilitate Antibiotic Sensitization of Enterococcus faecium

Published:2021-04-19 Issue:5 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Canfield Gregory S.¹²,Chatterjee Anushila²,Espinosa Juliel³,Mangalea Mihnea R.²,Sheriff Emma K.²,Keidan Micah²,McBride Sara W.²,McCollister Bruce D.¹,Hang Howard C.³⁴,Duerkop Breck A.²^ORCID

Affiliation:

1. Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado, USA

2. Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA

3. Laboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York, USA

4. Departments of Immunology & Microbiology and Chemistry, Scripps Research, La Jolla, California, USA

Abstract

Enterococcus faecium , a commensal of the human intestine, has emerged as a hospital-adapted, multidrug-resistant (MDR) pathogen. Bacteriophages (phages), natural predators of bacteria, have regained attention as therapeutics to stem the rise of MDR bacteria.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00143-21

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