Efficacy and Immune Correlates of OMP-1B and VirB2-4 Vaccines for Protection of Dogs from Tick Transmission of Ehrlichia chaffeensis-Reference-Cited by-同舟云学术

Efficacy and Immune Correlates of OMP-1B and VirB2-4 Vaccines for Protection of Dogs from Tick Transmission of Ehrlichia chaffeensis

Published:2022-12-20 Issue:6 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Budachetri Khemraj¹,Lin Mingqun¹,Chien Rory C.¹,Zhang Wenqing¹,Brock Guy Nathaniel²,Rikihisa Yasuko¹^ORCID

Affiliation:

1. Department of Veterinary Biosciences, College of Veterinary Medicine, Infectious Diseases Institute, Ohio State University, Columbus, Ohio, USA

2. Center for Biostatistics, Ohio State University, Columbus, Ohio, USA

Abstract

Ehrlichia are tick-borne pathogens that cause a potentially fatal illness—ehrlichiosis—in animals and humans worldwide. Currently, no vaccine is available for ehrlichiosis, and treatment options are limited.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Defense

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02140-22

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