Affiliation:
1. Division of Infectious Diseases, Miriam Hospital, Providence, Rhode Island 02906.
Abstract
Of 27 unique clinical isolates of methicillin-resistant Staphylococcus aureus, only 4 were homogeneously resistant, and all 4 produced little or no beta-lactamase. Among heterogeneously resistant strains, those most resistant to beta-lactam antibiotics produced the most beta-lactamase. Similar genes may regulate production of the low-affinity penicillin-binding protein and beta-lactamase.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference26 articles.
1. Acar J. F. P. Courvalin and Y. A. Chabbert. 1971. Methicillinresistant staphylococcemia: bacteriological failure of treatment with cephalosporins p. 280-285. Antimicrob. Agents Chemother. 1970.
2. Additional DNA in methicillin-resistant Staphylococcus aureus and molecular cloning of mec-specific DNA;Beck W. D.;J. Bacteriol.,1986
3. Reevaluation of the ability of the standardized disk diffusion test to detect methicillin-resistant strains of Staphylococcus aureus;Boyce J. M.;J. Clin. Microbiol.,1984
4. A methicillin-resistant strain of Staphylococcus aureus;Bulger R. J.;Ann. Intern. Med.,1967
5. La rdsistance naturelle des staphylocoques a la methicilline et l'oxacilline;Chabbert Y. A.;Rev. Fr. Etud. Clin. Biol.,1965
Cited by
18 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献