Mapping of trimethoprim resistance genes from epidemiologically related plasmids-Reference-Cited by-同舟云学术

Mapping of trimethoprim resistance genes from epidemiologically related plasmids

Published:1987-09 Issue:9 Volume:31 Page:1440-1441
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Campbell I G¹,Mee B J¹

Affiliation:

1. Department of Microbiology, Queen Elizabeth II Medical Centre, University of Western Australia, Nedlands.

Abstract

Trimethoprim resistance dihydrofolate reductase genes from plasmids known to be exchanging between human and animal populations were mapped. The dihydrofolate reductase gene has been highly conserved in all plasmids, but differences in the flanking regions provide evidence that the most recent exchange of plasmids between the two ecosystems has been from animals to humans.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.31.9.1440

Reference8 articles.

1. Nucleotide sequence of the dihydrofolate-reductase gene borne by the plasmid R67 and conferring methotrexate resistance;Brisson N.;Gene,1984

2. Evolution and spread of IncFIV plasmids conferring resistance to trimethoprim;Campbell I. G.;Antimicrob. Agents Chemother.,1986

3. Distribution of genes for trimethoprim and gentamicin resistance in bacteria and their plasmids in a general hospital;Datta N.;J. Gen. Microbiol.,1980

4. Monitoring of plasmid-encoded, trimethoprim-resistant dihydrofolate reductase genes: detection of a new resistant enzyme;Fling M. E.;Antimicrob. Agents Chemother.,1982

5. Trimethoprim resistance in multiple genera of Enterobacteriaceae at a U.S. hospital: spread of the type II dihydrofolate reductase gene by a single plasmid;Mayer K. H.;J. Infect. Dis.,1985

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1. Spread of a newly found trimethoprim resistance gene, dhfrIX, among porcine isolates and human pathogens;Antimicrobial Agents and Chemotherapy;1992-12

2. Interactions in Communities of Microorganisms;The Release of Genetically Modified Microorganisms—REGEM 2;1992

3. High genetic homology between plasmids of human and animal origins conferring resistance to the aminoglycosides gentamicin and apramycin;Antimicrobial Agents and Chemotherapy;1991-03

4. Trimethoprim resistance; epidemiology and molecular aspects: --a review based upon a Symposium held on 19 April 1989 at the 4th European Congress of Clinical Microbiology, Nice, France;Journal of Medical Microbiology;1990-01-01

5. Resistance to Trimethoprim;Handbook of Experimental Pharmacology;1989