Emergence of Oxacillin Resistance in Stealth Methicillin-Resistant Staphylococcus aureus Due to mecA Sequence Instability-Reference-Cited by-同舟云学术

Emergence of Oxacillin Resistance in Stealth Methicillin-Resistant Staphylococcus aureus Due to mecA Sequence Instability

Published:2019-08 Issue:8 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Goering Richard V.¹,Swartzendruber Erin A.¹,Obradovich Anne E.¹,Tickler Isabella A.²,Tenover Fred C.²

Affiliation:

1. Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA

2. Cepheid, Sunnyvale, California, USA

Abstract

Staphylococcus aureus strains that possess a mecA gene but are phenotypically susceptible to oxacillin and cefoxitin (OS-MRSA) have been recognized for over a decade and are a challenge for diagnostic laboratories. The mechanisms underlying the discrepancy vary from isolate to isolate.

Funder

Cepheid

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00558-19

Reference28 articles.

1. Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology

2. Is That Staphylococcus aureus Isolate Really Methicillin Susceptible?

3. Inducibility and potential role of MecA-gene-positive oxacillin-susceptible Staphylococcus aureus from colonized healthcare workers as a source for nosocomial infections