Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases in Enterobacteriaceae , Pseudomonas aeruginosa, and Acinetobacter baumannii
Author:
Affiliation:
1. Qpex Biopharma, Inc., San Diego, California, USA
Abstract
Funder
HHS | Biomedical Advanced Research and Development Authority
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Link
https://journals.asm.org/doi/pdf/10.1128/AAC.00552-20
Reference38 articles.
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3. The latest advances in β-lactam/β-lactamase inhibitor combinations for the treatment of Gram-negative bacterial infections
4. The Mechanism of High-Level Carbapenem Resistance inKlebsiella pneumoniae: Underlying Ompk36-Deficient Strains Represent a Threat of Emerging High-Level Carbapenem-ResistantK. pneumoniaewith IMP-1 β-Lactamase Production in Japan
5. Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae
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