The Intersection of Innate Immune Pathways with the Latent Herpes Simplex Virus Genome-Reference-Cited by-同舟云学术

The Intersection of Innate Immune Pathways with the Latent Herpes Simplex Virus Genome

Published:2023-05-31 Issue:5 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Cuddy Sean R.¹,Cliffe Anna R.²^ORCID

Affiliation:

1. Neuroscience Graduate Program, University of Virginia, Charlottesville, Virginia, USA

2. Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA

Abstract

Innate immune responses can impact different stages of viral life cycles. Herpes simplex virus latent infection of neurons and subsequent reactivation provide a unique context for immune responses to intersect with different stages of infection.

Funder

Owens Family Foundation

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Neurological Disorders and Stroke

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01352-22

Reference101 articles.

1. Kinetics of Facultative Heterochromatin and Polycomb Group Protein Association with the Herpes Simplex Viral Genome during Establishment of Latent Infection

2. Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters

3. Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation

4. Alphaherpesvirus Latency

5. Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus

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