Affiliation:
1. Radiological Research Laboratory, Department of Radiology, Columbia University, New York, New York
Abstract
Hill, Ruth
F. (Columbia University, New York, N.Y.). Relationship between ultraviolet sensitivity and ability to propagate ultraviolet-irradiated bacteriophage. J. Bacteriol.
88:
1283–1287. 1964.—Mutants with a reduced ability to propagate ultraviolet-damaged bacteriophage T
1
were isolated from
Escherichia coli
strain B/r. The change in this ability varied from a slight to a very marked loss; the greater the loss, the greater was the ultraviolet sensitivity of the mutant. Reduced ability to propagate irradiated T
1
appears to be the more sensitive index of genetic change, because in one mutant there was no significant reduction in ultraviolet resistance. In a converse study, second-step mutants with an increased ultraviolet resistance were obtained from a mutant of
E. coli
B. This mutant is both unable to propagate irradiated T
1
and very ultraviolet-sensitive. The increased ultraviolet resistance of the second-step mutants was not accompanied by an increased ability to propagate irradiated T
1
.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference17 articles.
1. Methods of study of bacterial viruses;ADAMS M. H.;Methods Med. Res.,1950
2. Isolation and identification of the irradiation product of thymine;BEUKERS R.;Biochim. Biophys. Acta,1960
3. Release of ultraviolet light induced thymine dimers from DNA in E. coli K-12;BOYCE R. P.;Proc. Natl. Acad. Sci. U.,1964
4. A host effect on bacteriophage survival after ultraviolet irradiation;ELLISON S. A.;Virology,1960
5. On the relationship between hostcell reactivation and UV-reactivation in UVinactivated phages;HARM W.;Z. Vererbungslehre,1963
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