Abstract
A new virus was found to be associated with acute gastroenteritis in children. In duodenal biopsies, it was observed infecting only intestinal epithelial cells, and it resembled orbiviruses in its morphogenesis. For diagnsotic purposes the virus was readily demonstrated by negative staining of fecal extracts. Two forms of particles were seen: double-sheeled particles (70 to 75 nm in diameter) resembling those of reovirus with a sharper outline, and single-shelled particles (60 nm in diameter) with obvious capsomer structure and resembling those of orbiviruses. The morphological resemblance of this human virus to the viruses of "Nebraska" calf scours and epizootic diarrhoea of infant mice is emphasized.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference31 articles.
1. Electronmicroscopic study of the intestinal epithelium of mice infected with the agent of epizootic diarrhea of infant mice (EDIM virus);Adams W. R.;Am. J. Pathol.,1967
2. Spontaneous degradation of reovirus capsid into subunits;Amano Y.;J. Virol.,1971
3. A study of the self-assembly process in a small spherical virus;Bancroft J. B.;Virology,1967
4. Further observations on the virus of epizootic diarrhea of infant mice-an electron microscopic study;Banfield W. G.;Virology,1968
5. Duodenal mucosal damage in 31 infants with gastroenteritis;Barnes G. L.;Arch. Dis. Child.,1973
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