Serological Reactions of Glycolipids from Streptococcal L-Forms

Author:

Feinman Susan Birnbaum1,Prescott Benjamin1,Cole Roger M.1

Affiliation:

1. Laboratory of Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014

Abstract

Parent bacteria and L-forms of some streptococci of group A, group D, and Streptococcus MG share common antigens as shown by cross-reactivity in growth inhibition, complement fixation, and Ouchterlony tests. Cross-reactivity between these streptococci or their L-forms with a staphylococcal L-form, or Mycoplasma pneumoniae , was found only rarely and only in low-titer complement fixation tests. Removal of all three serological reactivities from positive antisera by addition of chloroform-methanol (7:3) extracts of the streptococci or their L-forms, and failure to remove activities by protein extracts, indicated the glycolipid nature of the cross-reacting antigenic determinants.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference24 articles.

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4. Freimer E. H. 1968. Immunochemical properties of the protoplast membrane of group A streptococci p. 279-292. In L. B. Guze (ed.) Microbial protoplasts spheroplasts and L forms. The Williams & Wilkins Co. Baltimore.

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3. Synthesis of streptococci phosphatidyl-α-diglucosyldiglyceride and related glycolipids;Tetrahedron;1985-01

4. Solutions and Emulsions Used for Intravenous Infusions;Allergic Reactions to Drugs;1983

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