Affiliation:
1. Department of Microbiology, Chongqing University of Medical Sciences, Chongqing 400042, People’s Republic of China
Abstract
ABSTRACT
Chlamydia trachomatis
can synthesize glycogen at various stages in its developmental cycle. The glycogen content of female genital epithelial cells was detected by anthrone, and the results were compared with those from PCR. A total of 320 cervical samples were examined. Of 92 specimens that were positive by PCR, 78 were positive and 14 were negative by the glycogen assay. Of 228 specimens that were negative by PCR, 220 were negative and 8 were positive by the glycogen assay. The sensitivity and specificity of the glycogen assay obtained from these data were 84.8% (78 of 92) and 96.5% (220 of 228), respectively. Use of the glycogen assay to detect the glycogen content in genital epithelial cells may be helpful in the diagnosis of
C. trachomatis
infection. This is an easy, fast, and inexpensive assay and can be done in less-sophisticated labs.
Publisher
American Society for Microbiology
Cited by
67 articles.
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